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AI Can Now Design and Run Thousands of Experiments Without Human Hands. We Aren’t Ready for the Risk to Biosecurity.
The gap between what AI can do in biology and what governance systems are prepared to handle is growing.
Artificial intelligence is rapidly learning to autonomously design and run biological experiments, but the systems intended to govern those capabilities are struggling to keep pace.
AI company OpenAI and biotech company Ginkgo Bioworks announced in February 2026 that OpenAI’s flagship model GPT-5 had autonomously designed and run 36,000 biological experiments. It did this through a robotic cloud laboratory, a facility where automated equipment controlled remotely by computers carries out experiments. The AI model proposed study designs, and robots carried them out and fed the data back to the model for the next round. Humans set the goal, and the machines did much of the work in the lab, cutting the cost of producing a desired protein by 40 percent.
This is programmable biology: designing biological components on a computer and building them in the physical world, with AI closing the loop.
For decades, biology mostly moved from observation toward understanding. Scientists sequenced the genomes of organisms to catalog all of their DNA, learning how genes encode the proteins that carry out life’s functions. The invention of tools like CRISPR then allowed scientists to edit that DNA for specific purposes, such as disabling a gene linked to disease. AI is now accelerating a third phase, where computers can both design biological systems and rapidly test them.
The process looks less like traditional benchwork in a lab and more like engineering: design, build, test, learn, and repeat. Where a traditional experiment might test a single hypothesis, AI-driven programmable biology explores thousands of design variations in parallel, iterating the way an engineer refines a prototype.
As a data scientist who studies genomics and biosecurity, I research how AI is reshaping biological research and what safeguards that demands. Current safety measures and regulations have not kept pace with these capabilities, and the gap between what AI can do in biology and what governance systems are prepared to handle is growing.
What AI Makes PossibleThe clearest example of how researchers are using AI to automate research is AI-accelerated protein design.
Proteins are the molecular machines that carry out most functions in living cells. Designing new ones has traditionally required years of trial and error because even small changes to a protein’s sequence can alter its shape and function in unpredictable ways.
Protein language models, which are AI systems trained on millions of natural protein sequences, can quickly predict how mutations will change a protein’s behavior or design new proteins. These AI models are designing potential new drugs and speeding vaccine development.
Paired with automated labs, these models create tight loops of experimentation and revision, testing thousands of variations in days rather than the months or years a human team would need.
Faster protein engineering could mean faster responses to emerging infections and cheaper drugs.
The Dual-Use ProblemResearchers have raised concerns that these same AI tools could be misused, a challenge known as the dual-use problem: Technologies developed for beneficial purposes can also be repurposed to cause harm.
For example, researchers have found that AI models integrated with automated labs can optimize how well a virus spreads, even without specialized training. Scientists have developed a risk-scoring tool to evaluate how AI could modify a virus’s capabilities, such as altering which species it infects or helping it evade the immune system.
Current AI models are able to walk users through the technical steps of recovering live viruses from synthetic DNA. Researchers have determined that AI could lower barriers at multiple stages in the process of developing a bioweapon, and that current oversight does not adequately address this risk.
Risk From Bio AIExperienced scientists are already using AI to plan and design biological experiments. The question of whether AI can help people with limited biology training carry out dangerous lab work is the subject of active research.
Two recent studies have reached different conclusions.
A study by AI company Scale AI and biosecurity nonprofit SecureBio found that when people with limited biology experience were given access to large language models, which is the type of AI behind tools like ChatGPT, they were able to complete biosecurity-related tasks, such as troubleshooting complex virology lab protocols with four times greater accuracy. In some areas, these novices outperformed trained experts. Around 90 percent of these novices reported little difficulty getting the models to provide risky biological information, such as detailed instructions on working with dangerous pathogens, despite built-in safety filters meant to block such outputs.
In contrast, a study led by Active Site, a research nonprofit that studies the use of AI in synthetic biology, found that AI help did not lead to significant differences in the ability of novices to complete the complex workflow to produce a virus in a biosafety laboratory. However, the AI-assisted group succeeded more often on most tasks and finished some steps faster, most notably on growing cells in the lab.
Hands-on work in the lab has traditionally been a bottleneck to translating designs into results. Even a brilliant study plan still depends on skilled human hands to carry out. That may not last, as cloud laboratories and robotic automation become cheaper and more accessible, allowing researchers to send AI-generated experimental designs to remote facilities for execution.
Responding to AI-Driven Biological RisksAI systems are now able to run experiments autonomously and at scale, but existing regulations were not designed for this. Rules governing biological research do not account for AI-driven automation, and rules governing AI do not specifically address its use in biology.
In the US, the Biden administration had issued a 2023 executive order on AI security that included biosecurity provisions, but the Trump administration revoked it. Screening the synthetic DNA that commercial providers make to ensure it cannot be misused to make pathogens or toxins remains mostly voluntary. A bipartisan bill introduced in 2026 to mandate DNA screening does not yet address AI-designed sequences that evade current detection methods.
The 1975 Biological Weapons Convention, an international treaty prohibiting the production and use of bioweapons, contains no provisions for AI. The UK AI Security Institute and the US National Security Commission on Emerging Biotechnology have both called for coordinated government action.
The safety evaluations that AI labs run before releasing new models are often opaque and unsuited to capture real-world risk. Researchers have estimated that even modest improvements in an AI model’s ability to help plan pathogen-related experiments could translate to thousands of additional deaths from bioterrorism per year. Timelines for when these capabilities cross critical thresholds remain unclear.
The Nuclear Threat Initiative has proposed a managed access framework for biological AI tools, matching who can use a given tool to the risk level of the model rather than blanket restrictions. The RAND Center on AI, Security and Technology outlined a set of actions researchers could take to improve biosecurity, including improved DNA synthesis screening and model evaluations before release. Researchers have also argued that biological data itself needs governance, especially genomic data that could train models with dangerous capabilities.
Some AI companies have started voluntarily imposing their own safety measures. Anthropic activated its highest safety tier when it released its most advanced model in mid-2025. At the same moment, OpenAI updated its Preparedness Framework, revising the thresholds for how much biological risk a model can pose before additional safeguards are required. But these are voluntary, company-specific steps. Anthropic’s CEO, Dario Amodei, wrote that the pace of AI development may soon outrun any single company’s ability to assess the risk of a given model.
When used in a well-controlled setting, AI can help scientists quickly reach their research goals. What happens when the same capabilities operate outside those controls is a question that policy has not yet answered. Overreact, and talent and investment may move elsewhere while the technology continues advancing anyway. Underreact, and the risks of that technology could be exploited to cause real harm.
This article is republished from The Conversation under a Creative Commons license. Read the original article.
The post AI Can Now Design and Run Thousands of Experiments Without Human Hands. We Aren’t Ready for the Risk to Biosecurity. appeared first on SingularityHub.
Pink is the latest goon squad to use fake helpdesk calls to steal creds
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Microsoft makes Linux developers feel more at home in Windows with Coreutils release
Microsoft has announced Coreutils, a new Windows 11 feature that allows developers to run many popular Linux command line utilities natively on Windows from a single binary.
Revealed at this week’s Build 2026 developer conference in Seattle, Coreutils is about reducing what Microsoft terms the “cognitive load” faced by developers when moving between Windows and other platforms.
Currently, accessing the Linux command line utilities that are considered essential in many CI/CD development environments on Windows requires a kludge that involves either opening an emulation such as Git Bash, or a virtualized Windows Linux Subsystem (WSL) terminal.
Both are time-consuming and inefficient. As Microsoft’s announcement puts it: “Developers constantly move between platforms, but familiar commands don’t work consistently, forcing workarounds, lost speed and context switching.”
Coreutils removes the need for this back and forth, allowing developers to run most Linux commands straight from the Windows CMD command prompt, PowerShell, or Windows Terminal.
“Whether you’re moving between Linux, macOS, WSL, containers or cloud environments, the commands and workflows you’ve built over years just work in your Windows environment,” Microsoft said.
Most utilities, but not allInstalled as a single executable (via WinGet: install Microsoft.Coreutils), Coreutils for Windows itself is a Rust rewrite of the GNU uutils/coreutils project that provides commands that are universal across Linux distros.
Fundamental to making Coreutils efficient to manage is the fact that individual Linux commands run from a multi-call executable which maps via NTFS hardlinks pointing to each command. The advantage of this approach is that there’s only one binary to install, one binary to sign, and one binary to patch or update.
Microsoft lists 75 Linux utilities supported by Coreutils, including commonly-used commands such as ls, cp, find, grep, find, rm, du, hostname, and uptime.
However, some Coreutils commands clash with existing CMD or Powershell commands, or are otherwise not possible to execute; Microsoft provides a compatibility table listing conflicts. This means that some commands are not available, specifically: dir, expand, kill, more, timeout, and whoami.
There are also some commands omitted from Coreutils because a command relies on a POSIX Unix/Linux feature that Windows doesn’t implement in a compatible way; some examples are chmod, chown, id, stty, and chroot.
In other cases, the command will execute in one context, CMD, but not in PowerShell. Microsoft explained the complex order of precedence: “Whether the Coreutils version runs depends on the shell, the PATH order, and (for PowerShell) the alias table.”
As well as Coreutils, the Build 2026 developer conference also saw Microsoft announce WSL containers CLI and API to deploy Linux containers on Windows, a new framework for autonomous agents with open source governance tools, and Microsoft Scout, an AI agent designed to automate tasks in Microsoft 365.
This article originally appeared on InfoWorld.
Dashlane explains how attackers managed to download encrypted password vaults
Dashlane said that attackers mounted a coordinated hacking campaign against a large base of its users in an attempt to recover as many encrypted password vaults as possible. The password manager provider said fewer than 20 personal user vaults were downloaded before it shut down the operation.
In a campaign that started Sunday, the unknown threat actor abused the mechanism that allows Dashlane users to add new devices, such as computers or phones, to their accounts. By abusing Dashlane's programming interfaces for device enrollment, the attackers sent requests to large numbers of existing users’ registered email addresses. In an update published Thursday, Dashlane wrote:
The threat actor targeted the API endpoints for device registration and used a brute force attack to send a large volume of automated requests to those endpoints.
In response, Dashlane’s automated security systems operated as intended, triggering an automatic lockout of the targeted accounts to protect those users. Before the attack was fully mitigated, the threat actor was able to brute force and generate valid tokens for fewer than 20 personal plan customers, allowing them to register a new device on those accounts and download copies of users’ encrypted vaults.
The flow and strategy of the attackWhen a user installs the Dashlane app on a new device and attempts to enroll it in their existing account, Dashlane first verifies the account holder's identity. This verification is completed by sending a one-time six-digit token to the user’s registered email address (or, for users who have enabled two-factor authentication, by validating a six-digit code generated by their authentication app).
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Apple to open its first developer center in Europe
Apple in recent years has opened Apple Developer Centers in Cupertino, CA, Shanghai, Singapore, and Bengaluru to allow developers to meet, exchange ideas or get help from trained staffers.
It is now clear a new developer center will open in Europe, specifically in the German capital of Berlin, later this year. “Europe is home to an extraordinary community of developers who build apps that connect people, encourage creativity, and drive innovation,” says Susan Prescott, Apple’s vice president of Worldwide Developer Relations, said in a statement.
Developers will be able to receive support for their apps, regardless of whether they are built for iOS, iPadOS, macOS, tvOS, macOS, or watchOS.
The announcement comes just a few days before the company’s big Worldwide Developer Conference (WWDC) gets under way.
DentaQuest data breach exposed info of 2.6 million accounts
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