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ChatGPT Health lets you connect medical records to an AI that makes things up
On Wednesday, OpenAI announced ChatGPT Health, a dedicated section of the AI chatbot designed for "health and wellness conversations" intended to connect a user's health and medical records to the chatbot in a secure way.
But mixing generative AI technology like ChatGPT with health advice or analysis of any kind has been a controversial idea since the launch of the service in late 2022. Just days ago, SFGate published an investigation detailing how a 19-year-old California man died of a drug overdose in May 2025 after 18 months of seeking recreational drug advice from ChatGPT. It's a telling example of what can go wrong when chatbot guardrails fail during long conversations and people follow erroneous AI guidance.
Despite the known accuracy issues with AI chatbots, OpenAI's new Health feature will allow users to connect medical records and wellness apps like Apple Health and MyFitnessPal so that ChatGPT can provide personalized health responses like summarizing care instructions, preparing for doctor appointments, and understanding test results.
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WhatsApp Worm Spreads Astaroth Banking Trojan Across Brazil via Contact Auto-Messaging
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Texas court blocks Samsung from collecting smart TV viewing data
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Aging Weakens Immunity. An mRNA Shot Turned Back the Clock in Mice.
The treatment converted the liver into an immune cell “nursery” that pumped out greater numbers of healthy T cells.
Our immune system is a fierce brigade. Roaming immune cells scan for bacteria, viruses, and other invaders. They also communicate with tissues to catch early signs of cancer. After detecting a threat, the immune system kickstarts formidable defenses to snuff it out.
But our immunity loses power as we age. Immune cells dwindle, and those that remain struggle to perform their usual roles. As a result, immune defenses weaken, increasing the chances of infection and cancer. This also makes vaccines less effective in older adults.
Now, a new treatment using mRNA technology similar to that in Covid vaccines rejuvenated the immune systems of old mice with twice-weekly shots. The injections transformed the liver into a temporary nursery to boost the numbers and health of key immune cells.
Treated mice, aged the human-equivalent of their early 60s, saw a rapid rise in multiple T cell types after vaccination. They also rallied against tumors with a popular cancer immunotherapy.
Resetting immunity isn’t just about defense. The immune system is intricately tied to the health of other organs. Chronic inflammation steadily rises as we age, wreaking havoc on memory, cognition, and metabolism. It also stiffens tissues in multiple organs, increasing the chances of heart attacks and kidney failure.
“If we can restore something essential like the immune system, hopefully we can help people stay free of disease for a longer span of their life,” study author Feng Zhang at MIT said in a press release.
T Cell Boot CampMultiple immune cell types protect our bodies, but T cells are one of the most prominent.
Some T cells seek and destroy virus-infected cells and cancer. Others coordinate immune responses and balance the attack to prevent autoimmune problems or runaway inflammation. Still more “remember” prior threats to trigger a faster immune response when re-exposed.
Despite their wide range, all T cells are born in the bone marrow. Baby T cells then journey to the thymus, a small organ sitting at the top of the heart, where they mature and diversify. In this nursery, the cells learn friend from foe, ensuring they’ll only attack legitimate threats while leaving healthy cells alone. The process is mostly coordinated by cocktails of proteins and other signaling molecules, which direct the fate of immature cells and help them survive.
The aging process gradually degrades the nursery. The thymus shrinks, and much of its working tissue is replaced by fat, leading to a drop in newly minted T cells.
“As we get older, the immune system begins to decline. We wanted to think about how can we maintain this kind of immune protection for a longer period of time, and that’s what led us to think about what we can do to boost immunity,” said study author Mirco Friedrich.
For years scientists have tried to revive the organ. Hormones and immune-related proteins have struggled to bring it back to health. More exotic approaches, such as infusing the blood of young animals, transplanting stem cells, or directly tinkering with blood stem cells have shown some promise but are hard to turn into clinical treatments.
“Much has already been attempted to halt or reverse the age-related involution of the thymus,” said Friedrich. “Unfortunately, without much success so far.”
Rather than reviving the struggling organ, the team built a new T cell nursery in another part of the body.
Temporary HotbedThey began by comprehensively mapping genetic changes in infant and elderly mice and deciphering how shifts in gene expression influenced T cell production.
The screen surfaced three genes that play a critical role in T cell maturation. The proteins those genes produce fall with age, correlating with lower T cell numbers. Refreshing the proteins could, in theory, reboot immune cell production.
This “is more of a synthetic approach,” said Zhang. “We’re engineering the body to mimic thymic factor secretion.”
They decided on the liver as a temporary nursery for several reasons. The organ faithfully synthesizes proteins even into old age, and it’s a relatively easy target for mRNA treatments.
The team packaged mRNA encoding the three nurturing proteins into fatty nanoparticles and injected them into mice’s blood twice weekly for a month, beginning when the mice were aged the rough equivalent of people in their 60s. While far from elderly, T cell defects are noticeable around this age, and the cells could benefit from early intervention.
Compared to untreated peers, those given the shots produced more, healthier T cells. The treatment also boosted the critters’ immunity. In one test, mice vaccinated against ovalbumin, a major protein in egg whites, had a far stronger immune response against the protein compared to peers without the mRNA treatment.
The shots also helped the mice’s laggy immune systems better coordinate with checkpoint inhibitors, a common cancer medication. Mice with cancer given both treatments survived longer and at higher rates than those given only the inhibitors. More tests found all three protein-encoding mRNA sequences were needed to rejuvenate the immune system.
To be clear, this isn’t a one-and-done shot. The effects wane after treatment ends. While it seems like an inconvenience, the flexibility allows scientists to further tinker with dosage and treatment schedule and minimize side effects. More broadly, the study shows restoring the thymus isn’t necessary for turning back the clock on the immune system. Mimicking its signals in other parts of the body could also help T cells thrive, even in old age.
These are early results, and more tests are needed before bringing the therapy to people. The team plans to study the mRNA trio in other animals and hunt down more proteins that nurture T cells. They’re also looking to expand the strategy to other immune cell types, like the B cells that pump out antibodies.
“The immune system ages, but it does not irreversibly lose its abilities. If we provide it with the missing signals again, it can once more perform amazing feats,” said Friedrich.
The post Aging Weakens Immunity. An mRNA Shot Turned Back the Clock in Mice. appeared first on SingularityHub.
China-Linked UAT-7290 Targets Telecoms with Linux Malware and ORB Nodes
China-Linked UAT-7290 Targets Telecoms with Linux Malware and ORB Nodes
Ransomware attacks kept climbing in 2025 as gangs refused to stay dead
If 2025 was meant to be the year ransomware started dying, nobody appears to have told the attackers.…
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JP Morgan Chase wins the hunt for the Apple Card
Following many months of speculation, Apple has accepted JP Morgan Chase as the new issuer of Apple Card, replacing Goldman Sachs.
Apple has been on the hunt for a replacement card issuer ever since Goldman Sachs decided to abandon its push into retail banking. American Express, Synchrony Financial, and Capital One all expressed some interest in reaching the deal, but Chase took the prize.
Chase will become the new card issuer with the transition to the new arrangement expected to take around 24 months. Apple Card will continue to work as it already does in the meantime. Some things don’t change. While Chase replaces Goldman Sachs as card issuer, Mastercard will continue to act as the payment processor for the card.
‘Shared commitment’ for future of Apple CardFrom a highly enthusiastic start, Goldman Sachs seems to have become a less enthusiastic partner since deciding to abandon the retail banking market. This has likely prevented Apple from extending the card into new markets and building additional services for its financial product.
Jennifer Bailey, Apple’s vice president of Apple Pay and Apple Wallet, could be construed as having high hopes for the future, based on her Apple statement (italics mine): “Chase shares our commitment to innovation and delivering products and services that enhance consumers’ lives. We look forward to working together to continue to provide a best-in-class experience and exceptional customer service with Apple Card.”
“We’re excited to innovate together in the future,” said Allison Beer, Chase’s chief executive officer of Card & Connected Commerce.
Perhaps the biggest hint of expansive plans came from Mastercards’s president of the Americas, Linda Kirkpatrick, who said: “Innovation on Apple Card has taken the consumer payments experience to the next level, and we look forward to delivering simple, secure, and seamless payments at global scale.”
More challenging than beforeThe latter statement suggests an intention to make the service available more widely, though it’s possible the opportunity has already passed. Challenger banks are much more entrenched outside the US, even as international tension dents America’s singular brand appeal.
If you think back to the well storied launch of Apple Card, the world was quite different. At that time, the full impact of conflict and energy prices hadn’t struck and economies were in better shape. Apple hit that market with a cutting-edge financial product that attracted glowing praise from across consumers and the banking retail markets. JD Power’s vice president of banking and credit card services, Jim Miller, pointed out the opportunity that could be unlocked in emerging economies, where many were far more already accustomed to mobile banking services.
At the time of launch, Megan Caywood, Barclays’ global head of digital strategy, wrote, “Love seeing Apple nail the challenger bank playbook. It was recognized as the best US credit card by JD Power in 2021.
Unfortunately, early stumbles on the part of the new service, along with the decision to leave retail banking, put a brake on any plans that might have existed for a fast rollout of additional services, and the environment has changed.
That’s not necessarily a problem, given Apple’s vast brand appeal and the positive response its credit card service has already achieved. It is important to note that Chase is primarily a US consumer bank, which suggests the dream of an internationally available Appe Card could remain just that.
What about the detail?The deal ends years of speculation concerning the future of Apple’s $20 billion credit card portfolio. But getting there will take some time, with JP Morgan Chase putting aside $2.2 billion for potential credit losses during the move.
Goldman Sachs is also feeling some pain, taking a $1 billion loss on outstanding credit balances as part of the move. The truth seems to be that while Apple did attract lots of high-value customers — a 2020 survey claimed a third of Apple Card customers had annual incomes above $100,000 — it also attracted a hefty number of lower-income users and had user delinquency rates around 4%. (The industry average is 3.05%).
JP Morgan will also launch a new Apple savings account, though existing savers will be able to remain at Chase if they like.
Apple says the service will remain as it is, for now. That means no fees, 3% daily cash back, and useful tools such as Apple Card Family, installment payments, and savings. More information for existing Apple Card users is available here. The transition to Chase is subject to closing conditions and regulatory approvals, Apple confirmed.
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ChatGPT falls to new data-pilfering attack as a vicious cycle in AI continues
There’s a well-worn pattern in the development of AI chatbots. Researchers discover a vulnerability and exploit it to do something bad. The platform introduces a guardrail that stops the attack from working. Then, researchers devise a simple tweak that once again imperils chatbot users.
The reason more often than not is that AI is so inherently designed to comply with user requests that the guardrails are reactive and ad hoc, meaning they are built to foreclose a specific attack technique rather than the broader class of vulnerabilities that make it possible. It’s tantamount to putting a new highway guardrail in place in response to a recent crash of a compact car but failing to safeguard larger types of vehicles.
Enter ZombieAgent, son of ShadowLeakOne of the latest examples is a vulnerability recently discovered in ChatGPT. It allowed researchers at Radware to surreptitiously exfiltrate a user's private information. Their attack also allowed for the data to be sent directly from ChatGPT servers, a capability that gave it additional stealth, since there were no signs of breach on user machines, many of which are inside protected enterprises. Further, the exploit planted entries in the long-term memory that the AI assistant stores for the targeted user, giving it persistence.
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